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Kardiologiia ; 33(3): 12-4, 1993.
Article Ru | MEDLINE | ID: mdl-8377329

There was a relationship of the degree of imbalance between thromboxane and prostacyclin, prostaglandins (PG) F2 alpha and E1 in patients with coronary heart disease concurrent with stable angina pectoris. A significant increase in the levels of thromboxane and PGF2 alpha was found with relative prostacyclin and PGE1 deficiency during graded exercise at the moment of transient myocardial ischemia; the imbalance significantly increased as exercise tolerance decreased. Transient myocardial ischemia induced by transesophageal left atrial pacing revealed unidirectional changes in plasma PG, as did exercise.


Blood Platelets/physiology , Blood Vessels/physiopathology , Hemostasis , Myocardial Ischemia/blood , Physical Exertion/physiology , Rest/physiology , Adult , Angina Pectoris/blood , Angina Pectoris/physiopathology , Exercise Test , Exercise Tolerance/physiology , Humans , Male , Middle Aged , Myocardial Ischemia/physiopathology , Prostaglandins/blood
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